Shai Efrati

Dr. Shai Efrati is a professor at Sackler School of Medicine and the Sagol School of Neuroscience of Tel Aviv University and the director of the Sagol center for hyperbaric medicine and research at Shamir (Assaf-Harofeh) Medical Center in Israel. The center, under Prof. Efrati management, has become the largest hyperbaric center worldwide, currently treating more than 300 patients per day. Prof. Efrati is also the director of Research & Development at the Medical center, affiliated to Tel-Aviv University. Taking the two passions/positions together Prof. Efrati has initiated a research program focusing on the neuroplasticity (regeneration of damage brain tissue) looking at the brain as a tissue and characterizing the non-healing wounds in the brain and bottle necks that prevents their recover. In addition to diagnosis and characterizing, neuroplasticity can be induced using dedicated protocols of Hyperbaric Oxygen Therapy (HBOT). The newly used HBOT protocol induce brain and tissue repairment by fluctuations in oxygen and pressure that initiate regenerative biological cascade usually happens during hypoxia in hyperoxic condition- the so called Hyperoxic-Hypoxic paradox (HHP). The clinical studies proved that HHP can induce neuroplasticity in different types of brain injuries such as stroke, Traumatic Brain Injury, post-COVID, the so-called age-related cognitive decline, and central pain syndromes as Fibromyalgia syndrome.